Tri-Luma® is the only FDA-approved melasma treatment with 3 active ingredients, uniquely combined and more effective than treatments containing only two of the ingredients.
Tri-Luma® Cream is a unique triple-combination topical therapy for the short-term (8-week ) treatment of the dark spots associated with moderate-to-severe facial melasma.
- Fluocinolone acetonide 0.01% is a mild corticosteroid that reduces inflammation.
- Hydroquinone 4% is a depigmenting agent that interrupts the formation and synthesis of melanin to help lighten the skin.
- Tretinoin 0.05% works by increasing the skin cell turnover rate, which helps exfoliate the skin.
Tri-Luma® Cream should always be used in conjunction with sun-avoidance measures, like using sunscreens and wearing protective clothing. Tri-Luma® may improve the appearance of melasma but is not a cure.
IMPORTANT SAFETY INFORMATION
Indication: TRI?LUMA® Cream is indicated for the short?term (up to 8 weeks) treatment of moderate to severe melasma of the face in the presence of measures for sun avoidance, including the use of sunscreens. Adverse Events: In the controlled clinical trials, the most frequently reported events were redness, peeling, burning, dryness, and itching at the site of application. Warnings/Precautions: TRI?LUMA contains sulfites which may cause severe, life?threatening allergic reactions in people allergic to sulfites. TRI?LUMA contains hydroquinone, which may cause a gradual blue?black darkening of the skin. If you are pregnant, nursing or trying to become pregnant you should not use TRI?LUMA. Safety and efficacy have not been established in individuals with darker skin. Reversible HPA axis (adrenal function) suppression may result from exposure to the topical corticosteroid, fluocinolone acetonide, so discontinue use if signs and symptoms of this condition occur. Avoid products that may dry or irritate the skin, such as abrasive cleansers, scrubs, or skin?peeling agents. Exposure to sunlight, sunlamps, or UV light and extreme heat, wind, or cold should be avoided. If exposure cannot be avoided, sunscreen products [SPF 30 or more] and protective apparel should be used.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.